So you want to look like the Hulk or maybe you just want to be lean and muscular. So what's actually stopping you? Genetics... but what exactly is limiting your muscle growth, while at the same time limiting the burning of fat. Quite simply the answer is Myostatin. Myostatin is a direct negative regulator of the amount of skeletal muscle you have and how lean you are. Studies have proven this using mice with the myostatin knock out gene in which they don't have myostatin to limit muscle growth. These Mighty lean ripped mice are called double muscled and they look like mice on steroids, all without working out. The prized winning Belgian Blue and Piedmontese cattle have mutations of myostatin resulting in double muscling. Mutations in humans have been shown too have the same results.

Here are some myostatin links:

1) Myostatin Controlling Obesity and Insulin Resistance Obesity and insulin resistance

2) Muscle and MyostatinDouble muscling in cattle due to mutations in the myostatingene

3) Burn more Fat Suppression of body fat accumulation in myostatin-deficient mice

4) Myostatin in HumansChild with myostatin mutation



So what is CJC-1295 and what does it have to do with myostatin you ask... CJC-1295 is a long acting synthetic version of Growth Hormone Releasing Hormone (GHRH). 30mcg/kg to 60mcg/kg doses can increase gh levels up to 10X normal for 6 days or more with plasma IGF-1 concentrations by 3X for 9-11 days. The estimated 1/2 life is 5.8-8.1 days. After multiple doses the mean IGF-1 levels remain above base level for up to 28 days. Results show that 30mcg/kg CJC-1295 is equal to 5iu's of gh without the normal negative side effects from taking gh. In essence its much better to use CJC-1295 to make your body produce its own gh instead of taking a synthetic gh that also shuts down your normal production. So how does CJC-1295 and Myostatin relate. Growth hormone directly regulates myostatin. As growth hormone rises, myostatin lowers, which unleashes your potential for muscle growth. As myostatin lowers glucocorticoids effect on fat storage and muscle breakdown lowers. CJC-1295 dramatically raises gh levels which will dramatically lower myostatin which in turn will lower the effects of glucocorticoids fat storage and muscle breakdown. Now you know what has changed that has turned the Pro's into Freaks.

Studies to prove it:

1) Improve Cardiovascular Functions Growth Hormone and Cardiovascular Risk Factors

2) Get Lean & Muscular Growth Hormone Replacement Therapy Improves Body Composition

3) Burn FatGrowth Hormone–Releasing Hormone in HIV-Infected Men With Lipodystrophy

4) Dosing and resultsResults of CJC-1295 in Healthy Adults

5) Anabolic GH's direct anabolic effect from lowering Myostatin

6) Burn Fat-Retain MuscleLower Myostatin and prevent the catabolic effects of glucocorticoids

7) Prevent ObesityGlucocorticoids and Obesity

Read this study carefully, it will show that raising testosterone to supraphysiological levels increased pulsatile gh secretion. Supraphysiological is the key word here, cause anything less has no effect. Supraphysiological Test Levels increase GH

This study shows that androgens directly increase gh output without estrogen. Androgens directly increase GH

Raising Testosterone levels lowers Growth Hormone Binding Protein. This protein binds up excess gh. Testosterone lowering GHBP if you read the full text you will figure out that it's the spike in Test levels above normal from the shots that lowers GHBP proving that supraphysiological test levels raise gh and lowers GHBP

As you can see androgens can directly and indirectly raise growth hormone levels resulting in lowering Myostatin which you already learned increases muscle mass. On a side note leptin has a huge role in fat storage and as gh raises, leptin lowers. I won't delve into discussing leptin cause it can be complicated so do a search to learn more...

Lets go beyond muscle building and fat loss and discuss the well documented anti-aging benefits of growth hormone. Since this info is so plenty full online I'll only outline the known benefits and let you fulfill you quest for Anti-Aging by doing your own research. The rate of GH secretion from the pituitary gland is at its peak around puberty, declining progressively as we age beyond that point. Around the late 30s and throughout the 40s, GH levels continue to dip considerably, causing the telltale signs of aging to appear. Fat tissue begins to collect in areas where it may have not before, the skin begins to lose thickness, bone mass becomes depleted, energy levels drop, and mental clarity may become clouded.
For the purposes of anti-aging therapy, GH treatment functions to re-stimulate cell production to youthful levels restoring form and function to the entire body, from the inside out. Those who have undergone successful anti-aging treatment with GH or a combination of GH and other diminishing hormones such as testosterone have been reported to experience improvement in the skin’s appearance, renewed energy, mental acuity, invigorated health, enhanced sexual function, an overall sense of well being and a more youthful lean muscled look. Hundreds of studies have been done on the controlled administration of true HGH in adults. It has been shown to raise energy levels, enhance lean muscle development, decrease body fat, strengthen the heart, improve cholesterol and triglyceride levels and HDL/LDL ratios, fortify bones, smooth out skin wrinkles, sharpen memory, improve sexual function, regenerate damaged tissue, strengthen the immune system as well as improve sleep.
Somatotropin (HGH) from the pituitary gland works by stimulating protein production and synthesis in all tissues of the body. This results in an increase in organ healing and regeneration, which is associated with increase resistance to illness and injury.
In the skin, documentation regarding somatotropin (HGH) supplementation has shown increased collagen synthesis, which makes the skin thicker and smoother. In the bone, these studies showed increased bone density. In the internal organs and sex organs, research showed increased size and markedly improved function.
The immune system, research also showed increased immune system regulation and activity, resulting in fewer infectious illnesses. In adults, HGH is necessary for proper repair and regeneration of injured tissues.
One of the widely reported results of somatotropin (HGH) supplementation is the effect it has on the body's sexual centers. Research shows heightened desire and function in both men and women.
Beginning around the age of 20 years old, our natural production of somatotropin (HGH) begins to decline at the average rate of 14% per decade.
By the age of 40, somatotropin (HGH) production has decreased 30% over our youthful production level, and by the age of 60, by 80% on average. The decline in somatotropin (HGH) correlates with many of the effects of aging including loss of lean body mass (muscle, bone, skin and internal organs), increase in total body fat, thinning and wrinkling of skin, decreased immune function and decreased sexual desire and function.
As a result of the decline in somatotropin (HGH), and because it is the master hormone, other hormones also decline with age, such as Testosterone, Estrogen, Progesterone and DHEA, as well as many other important mood-elevating hormones. Examples of other hormones that also decrease are thyroid and thymus hormones, which can cause menopause in women and andropause in men.




So, gh therapy sounds great for anti-aging so what's the catch... The catch is keeping your levels in a physicological level and to not exceed youthful levels. As with any hormone, raising levels above youthful normal levels can cause unwanted side effects which are easily noticed like joint problems, the development of carpel tunnel and excess water weight gain. Its simple, just lower your dose if you notice a problem. There is a huge difference between keeping levels well above normal for years for anti-aging and doing a cycle with gh/cjc-1295 that exceed normal levels. Short term higher levels have much less potitential to cause long term problems... Ok, so you are interested in anti-aging with cjc-1295, what dose should you use. When taking into consideration the studies on it's outcome of gh production, as little as 1mg weekly is needed and no more then 2mg a week. This makes CJC-1295 extremely cost effective. Vials could be shared with fellow researchers if only 1mg is used weekly. The lab states after reconsituting cjc-1295 it can be refrozen to be used later but is best used without refreezing, so there may be a slight potiency loss by doing this.
In the studies 30mcg/kg or 60mcg/kg were used resulting in 2-10 fold in gh production. A 200lb man weighs aprox 90kg... thats 200 divided by 2.2 = 90 so thats 30mcg X 90=2700mcg=2.7mg or 60mcg X 90=5400mcg=5.4mg weekly these doses showed safety... I believe a minimum 2mg a week should be used and no more then 6mg... You decided but I say start low and work your way up to the dose you are comfortable with and remember to keep this short term to reach a specific goal and then go on an anti-aging dose between cycles which would also preserve the muscle growth you build during the cycle.

Shipping:
Vacuum sealed vials preserve the peptide and allow it to be shipped without ice packs. Peptides aren't as fragile as people make them out to be but you certainly want to put them in the fride when you receive them.
Storage: Refrigerate... 1yr + storage in the fridge
Reconstituted:After reconstituting with Bacteriostatic Water use within 3-5 days
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I just watched a show last night about the worlds strongest toddler and it had alot to do with myostatin,cant remember the exact specifics about it but the kid was like 3 times stronger than other 3 year old,zero body fat etc.....good show,this kids going to be awesome prob in any sport. thanks for the post

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I saw the same show last night. Lucky ass kid! lol

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ok, i am horrible at math, how many bottles would one need to run a "cycle" of this? I have never tried it but like what i read and may research it on my rats but i am a retard when it comes to mixing it in the water and taking the right amounts.

"and then go on an anti-aging dose between cycles" explain? Take me from the start and walk me thru the cycle....

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If you want my opinion and want to hear how I am running it now then here it is.

CJC 3x a day 100mcg each stick
GHRP-6 or 2 3x a day 250mcg each stick
you can combine them in the same insulin needle.

1 bottle of CJC has 2mg in it. So adding 2ml of Bacteriostatic water to it you would have 100mcg every 10iu. 3x a day protocol you would use 300mcg ED so one 2mg bottle would last you roughly 7 days.

1 bottle of GHRP-2 or 6 has 5mg in it. I add 2ml bacteriostatic water and that gives you 250mcg every 10iu. Doing it that way one bottle of 5mg will last you roughly 7 days.

Now if you want good results you want to do 3 shots ED 5 days a week and take the weekends off to avoid overloading the receptors or desensitization.

So for 2 months worth you would need around 6 bottles of each and that would give you 42 days worth of peptide not counting the weekends.

Also my ideal time to inject would be first thing in the morning then eat about 30 minutes later. Then inject 1 hour after drinking your post workout shake assuming you workout after 1pm or so. Last time to inject is right before bed to increase the GH response while asleep.

Sound good?

sounds almost as sexy as that ass in your avatar.

Thanks for the info, i will start stocking up.

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Good post.So all I need to do to increase GH/lower GHBP and decrease myostatin, is shoot up some androgens.Sounds cheap enough.
Thanks man

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If you can take this fucker running off at the mouth:

Super Human Radio Show - # 418 The GHRP Protocol from the Super Human Radio podcast

Something to look into and research for sure !

hhmm may order some of this soon

Awesome info! Thanks, def going to be trying this out!

OK so I have been doing a ton of reading and am wondering why the CJC needs to be dosed daily? or 5 on 2 off? It decays 10% daily. So why not 2x a week adminstered? then GHRP6 or 2 3x daily at 100mcg or 5 on 2 off?

I am assuming it would probably be most beneicial to run something like this for 6 months, however this seems like a long period if you account for the desensitization factor that can occur.. CJC is just a long acting form of GHRP. It will build up levels in your body. It seems desensitization is likely to occur, however I am not math savvy enough to calulate generally how long that will take to occur (plus it is very subjective - how quickly your receptors downregulate)

It seems almost impossible to find any info out there on administering IGF shots during a run of GHRP/CJC. Someone mentioned because it stimulates the pituitary gland, it would hinder the GHRP? How is that? I almost want to call BS. My thinking: IGF stimulates the pituitary to release more natty gh, and GHRP is a 'metabolite' so to speak of GH. (GH causes GHRP to be created secreted.) It would seem to me that they would then have a synergistic affect? IGF + GHRP = MORE GH and MORE GHRP?

Correct me if I am totally off here...

I would like to run 1 month IGF 30-40mcg eod bi lat, in bi's and
100mcg 3xd 5 days on 2 off GHRP with 300mcg cjc twice weekly ( Mon & Thurs.)

Ok whoa whoa whoa guys, I am tired.. I will explain ALL tomorrow.. please don't get ahead of yourselves here.. I KNOW EVERYTHING YOU NEED TO KNOW. I promise..

AND BB2K Bro, you never wanna cycle these peptides, they are almost as what you would call permanent replacement.. during anabolic phases though you would dose different; during cruise time.. the dosing protocol would be different than that if you were ON CYCLE..

Like I said, I shall explain all.. You don't need A LOT of each to get going.. in essence.. a bottle of CJC in the beginning can last you 30-40 days.. ghrp-2 (the best one- people see the 6 and automatically think it's better which isn't the case at all) well ghrp-2 will actually initiate a gh pulse.. and you can use CJC to extend the pulse, or use synthetic GH to slam a long pulse..

an example beginner:

Ghrp-2 50mcgs
10min later
1-4iu's of growth(however much you do...)

repeat process 4 times per day all 7 days of the week

CJC 100mcgs pre-bed or.. 100mcgs every 12 hrs. = 200mcgs per day.. or even 75mcgs every 12 hrs= 150mcgs per day..


I'll get into the schematics of it tomorrow when I am rested.. just read and absorb this for now.

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Any chance of more info or if you're going to be stocking this? Can it be run well on its' own or does it need to be stacked?

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Ok, I just ordered 3 5mg kits of GHRP-6. I have an idea how I will dose, but will I see any gains using alone? Should I be using the always scary slin with it?

This is my first run at a peptide like this so any advise is appreciated!!

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<< bigrobbie >>

IMO avoid the 'slin, it can be fatal if misused.

I've always felt that way too. Just trying to figure out the best peptide combo/stack. I'm a bit worried that GH peptides may not be worth the trouble.

I read good things, but not totally sure. I'm planning on 100mcg of ghrp-6 2X e.d. I ordered 3/5mg kits. Each kit is 5000mcg's if I'm correct. Should I run all 3 kits consectuive? Should I to 2 week on/2 weeks off?

Any input would be helpful. Is this planning stupid? SHould I run ghrp w/ another peptide? I may be overthinking, but Ive read so many different things Ive confused myself!

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<< bigrobbie >>

You've bought exactly the same as me lol. I'm starting my shots on their own just to try and guage any effects I get with them but will then be running it into my next cycle as well. Only thing that concerns me is the increase in appetite and I don't really have problems eating.

Check this review out...confirms what you just said.

Growth Hormone Releasing Peptide 6 (GHRP-6) Profile

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<< bigrobbie >>

I wanna run these 2 together asap. I have heard nothing but great reviews on it!

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