Ok so if you are like me when I cycle I want to get the most benefits possible from the compounds I am using, and we all know how much easier it is to use something orally vs injectable. I have thought long and hard about what the difference would be if any on just orally drinking my winnie vs injecting it. Questions I ask myself are, am I going to be getting the same amount absorbed orally that I would be by injecting this compound? The same benefits? Do I need to dose more orally than I would inject, because of the way it's entering my system? What about the benefits of local growth from the injection site, is it really worth loosing this by drinking it? I think you get the idea, I am sure some of you wonder the same!! Especially if you Buttocks are turning into a pin cushion from your cycle you are using!! I'm also curious because the last person I discussed this with told me I need to ingest double the dosage orally that I would inject in order to get the same dosage. Know I had a little debate with him over this, as I would think this would vary from person to person depending on metabolic rates, size, and over all health. He couldn't give me any straight answers and back them up with any proof of the matter. Also I would tend to think that if you take this orally you should take what you would dose it in, and break it into smaller doses thru out the day, so its much easier on you liver, your blood levels stay at constant levels, without going drastically up and down, and you would benefit more from this rather than one large dose.
So I always ask those that I know are more educated on this matter and always look on the internet for some sort of research or testing that may be beneficial in learning about this. So here's some information I have found and want to share. As well as ask everyone if they have anything to add or thoughts, questions on this matter.
I got this from an article written by Brock Strasser, who writes a column for a magazine.
Q: There's this huge debate raging over whether or not you can "drink" your Winstrol - stanozolol-V. I know that because stanozolol is 17 alpha-alkylated'ed, I can use it orally. However, how much more or less effective is oral stanozolol over injected stanozolol? I hear that you need about twice as much stanozolol orally as you would injected to see similar results. How was this figure of doubling the dose orally determined?

A: There isn't a lot of great pharmacokinetic data in humans comparing oral to parenteral (injectable) stanozolol. So that idea of "if you use X amount by injection you need twice as much orally" is anecdotal and speculative at best. The best I could find is a study comparing the two methods of administration in dogs. My comments come after the abstract:

The effect of stanozolol on 15-nitrogen retention in the dog

Can J Vet Res 2000 Oct;64(4):246-8 (ISSN: 0830-9000)

Olson ME; Morck DW; Quinn KB [Find other articles with these Authors] Animal Health Unit and Gastrointestinal Sciences, University of Calgary, Alberta.

The objective of the study was to determine the influence of either oral or intramuscular administration of stanozolol on nitrogen retention in dogs by using a non-invasive 15N-amino acid tracer technique. Ten healthy, intact, adult male sled dogs received either stanozolol tablets, 2 mg/dog PO, q12h, for 25 days (Group 1, n = 5) or an intramuscular injection of 25 mg of stanozolol on Days 7, 14, 21, and 28 (Group 2, n = 5). A 15N amino acid (5.27 mmol) was infused intravenously into each dog on Day 0 (before stanozolol treatment) and on Day 31 (after stanozolol treatment). Urine was collected by catheterization from each animal 3 times daily for 3 consecutive days. The 15N-urea enrichment in urine was determined by high-resolution mass spectrometry and the total amount of urea in the urine was determined.

Both oral and injectable stanozolol resulted in significant (P < 0.05) increases in amino acid nitrogen retention compared to pretreatment values. Oral stanozolol increased nitrogen retention from 29.2 +/- 8.2% to 50.3 +/- 9.2%, while stanozolol injection increased nitrogen retention from 26.6 +/- 9.9% to 67.0 +/- 7.5%. The response to intramuscular administration was significantly greater than the response to the oral dosing regime. Stanozolol increases amino acid nitrogen retention in dogs, as has been previously observed in rats. This action of stanozolol may be beneficial in dogs under stress of surgical trauma and chronic disease.

Okay, so the oral dose was 28mg/week and the injected dose was 25mg/week. And the injected dose was far better at increasing nitrogen retention (67.0% versus 50.3%). This makes it about 33.2% better (roughly speaking), so if I extrapolate, it means to see the same effects as 25mg of injected stanozolol per week, you'd need to take about 38mg of it orally.

This isn't quite "twice the injected dose" and is, in fact, closer to 50% (52% or so actually). So if you assume the dog model is correct, or nearly so in other mammals like humans, you'd need about 50% more stanozolol orally than you would if you injected it. So if you used 50mg of injected Winstrol every other day, it would be a safe bet to assume 37.5mg of stanozolol used orally every day would provide a similar effect.




So after reading this, I am still controversial on whether to drink or inject. In my logic is seems I would get more from injecting it and it will be easier on my liver, especially if I am using another oral at the time.

What do you all think?


Stay Strong~~!!!
IPL

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Injection

I think it hurts to inject and when I was running 4 other compounds it was easier to drink then add another hole!
But if your using another oral your liver will thank you if you shoot it!

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The Left Hand Lands And The Right Hand Devastates


*DESTROY EVERYTHING*

fuck the pain....i hated inj winny..feels like a baseball bat hit whatever you inject. Some NAC + Milk T. and your good! ORAL for me...lol

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SGT/2311/USMC

Injective for some reason I like more.

I have seen this study before. I like it, but you have to take it with a grain of salt. Yes, it shows a higher nitrogen retention when injected vs being injested, you have to take into account the differences in anatomy between dogs and humans. The dogs body is made to clean any and everything that enters the body at a much higher level than humans. Our bodies gave up that ability when we became civilized and learned how to cook our food (hence why we can live without our appendix which is used to fight bacteria from food we consumed). Not only is the dogs ability to "filter" food much higher than ours, its stomachs ph level is also more acidic compared to ours. Basically, a dog would have to take several times the dose a human would (in relation to mg-bodyweight) to have the same interactions in the body.
We have to remember that chemically, winny is winny whether it is injected or injested. There is no difference in the make up, so however we take it, it has to bypass the liver. Yes, the stomach does destroy a SMALL amount of the compound before it hits the liver (which can be halted to a larger degree by taking the medication with a glass of grapefruit juice which slows the release of the chem from the stomach so the body can absorb more of it) it is close to the same amount as an injection.
Basically, however you take it, its going to hit your liver. And it will be close to the same amount. No way around it

Well ^^^thats why its such a great debate~!!! I have tried it both ways and I feel for me I have much better results with inject, rather than oral. So its just what ever one prefers.
I always add B12 to my injections, makes them go in much smoother and less pain during and after.

Stay Strong~~!!!
IPL

__________________
OBAMA
O one B bad A ass M mistake A America

NO RESOLUTIONS~!! JUST SOLUTIONS~!!
STAY STRONG AND HEALTHY~!

PAIN IS WEAKNESS LEAVING THE BODY~

http://www.xtremebodybuilding.net/in...referrerid=146

I would inject aslo...but Im not a fan of winny to begin with so I dont use it...